Individual and combined effects of leaves and flowers extracts of Cassia glau-ca on membrane stabilization, antimicrobial and antioxidant activities

  • Deepak Kumar Department of Pharmaceutical Chemistry, Dolphin PG Institute of Biomedical and Natural Sciences, Dehradun, Ut-tarakhand, India
  • Abhishek Singh Department of Pharmaceutical Chemistry, Dolphin PG Institute of Biomedical and Natural Sciences, Dehradun, Ut-tarakhand, India
  • Ashwani Sanghi Department of Biochemistry, Dolphin PG Institute of Biomedical and Natural Sciences, Dehradun, Uttarakhand, India
  • Raju Chandra Department of Chemistry, Dolphin PG Institute of Biomedical and Natural Sciences, Dehradun, Uttarakhand, India
  • Shefali Arora Department of Chemistry, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, India.

Abstract

Herbal drug are used all over the world including traditional medicinal sytems. Many traditional systems are using herbal medicine from old age. In the present study, different extract were prepared from leaves and flower of Cassia glauca and evaluated for membrane stabilizing, antimicrobial and antioxidant activities. The methods for the same were done by hypotonic induced haemolysis, well diffusion and DPPH methods respectively. Combined effect of leaves and flowers extracts of Caasia glauca were also checked for their synergestic effect at a ratio of concentration 1:1 (w/w). The results indicated that the maximum membrane stabilizing activity 55.53±0.83% was showed by methanol extract of flower. A significant inhibition zone in antibacterial activity was measured by combined methanol extract of flower and leaves, acetone extract showed maximum antifungal activity, and flower extract of methanol showed maximum antioxidant activity 92.55±0.41 %. Further investigation are needed for isolation of the bioactive principle.                

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Published
2017-06-21
How to Cite
KUMAR, Deepak et al. Individual and combined effects of leaves and flowers extracts of Cassia glau-ca on membrane stabilization, antimicrobial and antioxidant activities. International Journal of Research in Pharmaceutical Sciences, [S.l.], v. 8, n. 2, p. 129-134, june 2017. ISSN 0975-7538. Available at: <https://www.pharmascope.org/index.php/ijrps/article/view/890>. Date accessed: 24 sep. 2017.
Section
Research Articles
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