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The methanol extract of Marsilea quadrifolia Linn is explored aimed for the first time for anti-venom activity. The Marsilea quadrifolia Linn extract extensively antagonized Russell’s viper venom-induced lethality, haemorrhage, necrotizing, defibrinogenating and paw edema activities were extensively neutralized by plant extract. The above explanation confirmed that methanol extract of Marsilea quadrifolia Linn acquire persuasive snake venom neutralizing capability and could theoretically be used for therapeutic rationale in case of snakebite envenomation.
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