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Abstract

Computed tomography is commonly used for the initial diagnosis of a tumour to provide information about the stage of cancer & to assess whether the disease is responding to treatment. Leukemia & solid tumour may have developed as a result of exposure to a low dose of diagnostic ionizing radiation so another primary tumour may develop as a result of radiation exposure. We used information in the patient sheet to measure patient effective radiation dose(E) in millisievert (mSv) & calculate cumulative dose by summation of dose over three years, estimated life attributed risk & mortality rate. The results of the current study revealed that from 50 patients 37 (74%) of them were female & 13 (26%) of them were male, age range 23- 80yr, breast cancer was the commonest cause of malignancy follow by lung cancer. Cumulative dose in mSv/yr rang 12-80 mSv, about 43(86%) of our patients exposed to more than 20mSv /yr & 7(14%) of them expose to 20 & less than 20 per year. Collective dose in three years’ range was 35-250 mSv mean 97 ± 37 Estimated radiological effective dose was more than 100 mSv in 22 (44%) per three years & 28(56%) of them had less than 100mSv. Life attributed risk for incidence of cancers was 1:285 -1:40 & mortality rate 0.21%-1.5%. A high percentage of patient 86% with cancer receive high radiation dose annually from CT scan more than considerable safe radiation dose for a worker in this field and 44% of our patient expose to cumulative dose more than 100 mSv per three which is also excess allowed dose for the radiological worker.

Keywords

Radiation dose Computed tomography Malignancy Mortality rate

Article Details

How to Cite
Amjaad Majeed Hameed, & Dergham Majeed Hameed. (2019). Biological effective dose, cumulative radiation dose, risk of malignancy and mortality rate estimation in adult patients who have a history of cancer and exposed to recurrent computed tomography. International Journal of Research in Pharmaceutical Sciences, 10(2), 1405-1409. https://doi.org/10.26452/ijrps.v10i2.585