Antibacterial susceptibility profile of Pseudomonas aeruginosa in a private hospital, India

  • Chandrasekaran K Department of Pharmacy Practice, KMCH College of Pharmacy, Coimbatore, India
  • Gandhiraj D Department of Microbiology, Kovai Medical Center and Hospital, Coimbatore, Tamil Nadu, India
  • Guru Prasad Mohanta Department of Pharmacy, Annamalai University, Chidambaram, Tamil Nadu, India
  • Rajasekaran A Department of Pharmacy Practice, KMCH College of Pharmacy, Coimbatore, India

Abstract

P. aeruginosa is a cosmopolitan gram-negative aerobic bacillus isolated from soil, water, plants, and animals, including humans. It is occasionally pathogenic for plants as well as animals. P. aeruginosa is an opportunistic pathogen with innate resistance to many antibiotics and disinfectants. It rarely causes disease in healthy persons, although it is a common human saprophyte. P. aeruginosa is physiologically versatile and flourishes as a saprophyte in multiple environments, including sinks, drains, respirators, humidifiers and disinfectant solutions. Prevalence of Pseudomonas Aeruginosa(PA) among the positive cultures is found to be 11.5%, 10.1% and 11% in 2012, 2013 and 2014 respectively. The number of isolates reduced in the consecutive years and saw an increase in the last year. The number of isolates was found to be more in the ICU than in the wards. In the current study, there were no resistant strains identified neither in the wards nor ICU. The susceptibility of isolates of PA to antibiotics remains slightly higher in all the three years. Susceptibility of PA has decreased substantially to Gentamycin, Amikacin, Meropenem respectively in the second year but showed a gradual increase in the susceptibility in the final year. Results from a larger, well-monitored surveillance network, can provide useful information by detecting signs of emerging pathogen populations/resistance patterns as well as trends in antimicrobial resistance mechanisms.

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Published
2019-01-05
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How to Cite
Chandrasekaran K, Gandhiraj D, Guru Prasad Mohanta, & Rajasekaran A. (2019). Antibacterial susceptibility profile of Pseudomonas aeruginosa in a private hospital, India . International Journal of Research in Pharmaceutical Sciences, 10(1), 298-302. Retrieved from https://www.pharmascope.org/index.php/ijrps/article/view/50
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Original Articles
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