Main Article Content

Abstract

The outbreak of 19 is now a pandemic affecting population pan . It has challenged the health system at various levels such as case identification, diagnostic laboratory workup, management and treatment and the epidemiological aspects of preventive interventions. It is so because this viral infection has never ever been encountered . The is a single stranded RNA virus with a few peculiarities of structure such as spike (S). This structural protein has been attributed to of 19 infections. The transmission of 19 is by droplets and aerosol. It primarily affects lungs, and its binding sites are cellular receptor of ACE II of . The and fatalities associated to Covid-19 infection are attributed to storm. It chiefly affects lungs producing . There are other manifestations of 19 infections. The diagnosis of 19 infection is by PCR of swab and samples from trachea and bronchi. The antibody (IgM and IgG) testing too is advised but as auxiliary in support of diagnosisThe hematological manifestations and biochemistry of the blood helps in suspecting and predicting the course of 19 infection. The present review imbibes within it, the various scientific nuances of novel corona virus that introduces -19 infection and explains the characteristics of the virus, and storm, immune evasion lung injury alteration laboratory diagnosis, , parameters of significance in laboratory of viral RNA and the proposed model of laboratory evaluation of 19 infection. The review provides a model for resource limited hospital at screening and confirmation of 19 infectionswhich will simplify, augment and enable the necessary hospital services and corrective therapeutic interventions.

Keywords

Covid – 19 Virus Pathogenesis Diagnostic Laboratory Model

Article Details

How to Cite
Sophia Thomas, Akriti Jain, Divya P Mohan, Arzoo R Alagh, Shweta Pandey, & Arvind Bhake. (2020). The medical laboratory prosecution of Covid – 19: pathogenesis and diagnosis. International Journal of Research in Pharmaceutical Sciences, 11(SPL1), 1089-1098. https://doi.org/10.26452/ijrps.v11iSPL1.3540