Analysis of Hydroethanolic leaf extract of Aerva lanata (L.) in screening an-tioxidant activity and in vitro antibacterial efficacy

  • Lucia Sounder Research & Development Centre, Bharathiar University, Coimbatore -641 033, Tamil Nadu, India
  • Doss VA Department of Biochemistry, PSG College of Arts and Science, Coimbatore -641033, India
  • Mohanasundaram S Department of Biotechnology, Karpaga Vinayaga College of Engineering and Technology, Maduran-thagam – 603308, Kanchipuram District, Tamil Nadu, India

Abstract

The present investigation has been carried out to evaluate antioxidant and antibacterial activity of ethanolic leaf extract of Aerva lanata L. The extracts were screened for their in vitro antioxidant potential Inhibition of oxygen-derived free radicals, viz., assays for free radical scavenging by DPPH, SOD, OH and nitric oxide scavenging were performed. In this study, the plant showed substantial antioxidant activities as resembling standard (i.e. ascorbic acid). The highest antioxidant activity was observed and could be attributed due to the presence of flavonoids and saponins. Ethanolic extract of Aerva lanata L was further subjected to antibacterial assessment. It was found that plant extract showed significant antibacterial efficacy, especially on Pseudomonas aeuroginosa against standard Streptomycin at 10 µg. Thus, ethanolic leaf extract of Aerva lanata L. showed high efficiency of antioxidant and antibacterial activity due to the presence of various phytochemicals. Some of the active principles of bioactive compounds are preferred for their therapeutic purposes either singly or in combination to inhibit the life processes of microbes bacterial efficacy.

Keywords: Aerva lanata, Phytochemical, Antioxidant, Antibacterial

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Published
2018-07-12
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How to Cite
Lucia Sounder, Doss VA, & Mohanasundaram S. (2018). Analysis of Hydroethanolic leaf extract of Aerva lanata (L.) in screening an-tioxidant activity and in vitro antibacterial efficacy. International Journal of Research in Pharmaceutical Sciences, 9(3), 911-915. Retrieved from https://www.pharmascope.org/index.php/ijrps/article/view/341
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Original Articles
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