Synthesis, characterization and pharmacological activity of new 2- imino –thiazolidine-4-one derivatives

  • Raghdah M. Alwiswasy Department of Pharmaceutical Chemistry, Pharmacy College, Basra University, Basrah, Iraq (IQ)
  • Raheem Jameel M Department of Pharmaceutical Chemistry, Pharmacy College, Basra University, Basrah, Iraq (IQ)
  • Basim Jasim Hameed Department of Clinical Laboratories Sciences, Pharmacy College, Basra University, Basrah, Iraq (IQ)

Abstract

A new 2-iminothiazolidin-4-ones compound and its derivatives were synthesized and characterized by FT-IR, CHN, and 1HNMR techniques. The target compounds were assessed for their anti-inflammatory and analgesic activities, and the study was performed using Swiss albino mice (25-30 g) for investigation. A hind edema model caused by , while the analgesic activity was assessed using an acetic acid-induced writhing and a hot plate test evaluated the anti-inflammatory activity.

Keywords: Inflammatory, 2-iminothiazolidin-4-ones, synthesis, anti-inflammatory, analgesic

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Published
2019-07-12
Citations
How to Cite
Raghdah M. Alwiswasy, Raheem Jameel M, & Basim Jasim Hameed. (2019). Synthesis, characterization and pharmacological activity of new 2- imino –thiazolidine-4-one derivatives. International Journal of Research in Pharmaceutical Sciences, 10(3), 1763-1769. https://doi.org/10.26452/ijrps.v10i3.1369
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Original Articles
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