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This study was conducted to isolate some bacteria from different clinical infectious sources and determine the antibiotics susceptibility pattern usually used for the treatment of these related bacteria. From the period March 2016 to August 2016, a total of 135 different clinical specimens such as urine (50) specimens, wound (45) specimens, blood (15) specimens, and sputum (25) specimens were collected from different hospitals at Baghdad City. Iraq. K. pneumoniae isolates showed the following percentage of resistance; Cotrimoxazole 100 %, ceftazidime 61.1 %, aztreonam 38.9 %, piperacillin 100 %, ciprofloxacin 66.7 %, amikacin 22.3 %, gentamycin 27.8 %, Also K. pneumoniae isolates showed no resistance to the antibiotics imipenem and meropenem. P. aeruginosa isolates showed frequency resistance profile; cotrimoxazole 100 %, ceftazidime 90 %, aztreonam 70 %, piperacillin 100 %, ciprofloxacin 30%, amikacin 80 %, gentamycin 80 %, while P. aeruginosa isolates showed low resistance to the antibiotics imipenem and meropenem 20 %, 10 % respectively. P. mirabilis isolates showed the following percentage of resistance; cotrimoxazole 83.3%, ceftazidime 66.7 %, aztreonam 66.7 %, piperacillin 100%, ciprofloxacin 16.7 %, gentamycin 30.8 %, while P. mirabilis isolates showed no resistance to the antibiotics amikacin, imipenem and meropenem. The most recurrent pathogen isolated from different specimens in this study was Escherichia coli (31) (40.3%), followed by Klebsiella pneumoniae (18) (23.4%), Pseudomonas aeruginosa (10) (13%), P. mirabilis (6) (7.8%). All the isolates showed high resistance rate of 100 % to piperacillin.
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