Main Article Content

Abstract

The antihyperglycemic activity of ethanolic extract of Portulaca pilosa Linn. was evaluated against streptozotocin-induced diabetic rats. The blood glucose levels were calculated at various time intervals of 0, 1, 2 and 3 h after the administration of ethanolic extract of P.pilosa. The ethanolic extract reduced the blood glucose levels significantly when it was administered at three doses of 100, 200 and 400 mg/kg. It reduces the blood glucose level from 334.67±5.27 to 134.57±6.49 at 3h after the administration of 200 mg/kg of ethanolic extract. The antihyperglycemic activity was evaluated in comparison of the administration of an oral hypoglycemic agent, Tolbutamide.

Keywords

Portulaca pilosa Antihyperglycemic Streptozotocin

Article Details

How to Cite
Arul Balasubramanian, Vijayarangan Sivasamy, Manivannan Ekambaram, & Kothai Ramalingam. (2019). Antihyperglycemic effect of Portulaca pilosa Linn. in streptozotocin-induced diabetic rats. International Journal of Research in Pharmaceutical Sciences, 10(1), 673-676. Retrieved from https://pharmascope.org/ijrps/article/view/123